Fortune 500 and Fortune 1000 Companies in Chicago

As of 2026, there are currently 14 Fortune 500 companies and 24 Fortune 1000 companies headquartered in Chicago, Illinois. These companies in total generate $414.35B in annual revenue, $39.91B in annual profit and employ 827.47K people.

A Fortune 500 company is one of the 500 largest corporations in the United States, ranked by total revenue for their respective fiscal years. These companies are known for their significant influence on the economy, often leading their industries and driving innovation and job creation. The Fortune 1000 list expands on this by including the top 1,000 companies, offering a broader perspective on the nation's corporate landscape.

Chicago, Illinois is a key center for corporate headquarters, home to numerous Fortune 500 and Fortune 1000 companies that contribute to its vibrant economy. The city's strong financial sector, diverse industries, and well-established infrastructure make it a vital business hub in the Midwest. Its access to global markets, extensive transportation network, and highly skilled talent pool attract companies from industries such as finance, logistics, healthcare, and manufacturing. These businesses not only fuel economic activity but also enhance Chicago's reputation as a global business center.

In this article, we explore the top Fortune 500 and Fortune 1000 companies with headquarters in Chicago, offering an in-depth look at their contributions to the local economy. Along with key data on revenue and industries, we also examine how these companies shape Chicago's role as a leader in innovation, sustainability, and job creation.